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GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells

The role of the alternate G protein–coupled estrogen receptor 1 (GPER1) in colorectal cancer (CRC) development and progression is unclear, not least because of conflicting clinical and experimental evidence for pro- and anti-tumorigenic activities. Here, we show that low concentrations of the estrog...

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Detalles Bibliográficos
Autores principales: Bühler, Miriam, Fahrländer, Jeanine, Sauter, Alexander, Becker, Markus, Wistorf, Elisa, Steinfath, Matthias, Stolz, Ailine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670797/
https://www.ncbi.nlm.nih.gov/pubmed/36384894
http://dx.doi.org/10.26508/lsa.202201499