Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing

BACKGROUND: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system to which a genetic predisposition contributes. Over 200 genetic regions have been associated with increased disease risk, but the disease-causing variants and their functional impact at the molecul...

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Detalles Bibliográficos
Autores principales: Putscher, Elena, Hecker, Michael, Fitzner, Brit, Boxberger, Nina, Schwartz, Margit, Koczan, Dirk, Lorenz, Peter, Zettl, Uwe Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670805/
https://www.ncbi.nlm.nih.gov/pubmed/36405756
http://dx.doi.org/10.3389/fimmu.2022.931831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670805/
https://www.ncbi.nlm.nih.gov/pubmed/36405756
http://dx.doi.org/10.3389/fimmu.2022.931831

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