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Genetic risk variants for multiple sclerosis are linked to differences in alternative pre-mRNA splicing

BACKGROUND: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system to which a genetic predisposition contributes. Over 200 genetic regions have been associated with increased disease risk, but the disease-causing variants and their functional impact at the molecul...

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Detalles Bibliográficos
Autores principales:	Putscher, Elena, Hecker, Michael, Fitzner, Brit, Boxberger, Nina, Schwartz, Margit, Koczan, Dirk, Lorenz, Peter, Zettl, Uwe Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670805/ https://www.ncbi.nlm.nih.gov/pubmed/36405756 http://dx.doi.org/10.3389/fimmu.2022.931831

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