Experimental evidence for the correlation between RNA structural fluctuations and the frequency of beneficial mutations

RNA has been used as a model molecule to understand the adaptive evolution process owing to the simple relationship between the structure (i.e., phenotype) and sequence (i.e., genotype). RNA usually forms multiple substructures with similar thermodynamic stabilities, called structural fluctuations....

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Detalles Bibliográficos
Autores principales: Maeda, Yutaro, Mizuuchi, Ryo, Shigenobu, Shuji, Shibai, Atsushi, Kotani, Hazuki, Furusawa, Chikara, Ichihashi, Norikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670806/
https://www.ncbi.nlm.nih.gov/pubmed/36195345
http://dx.doi.org/10.1261/rna.079291.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670806/
https://www.ncbi.nlm.nih.gov/pubmed/36195345
http://dx.doi.org/10.1261/rna.079291.122

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