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Experimental evidence for the correlation between RNA structural fluctuations and the frequency of beneficial mutations
RNA has been used as a model molecule to understand the adaptive evolution process owing to the simple relationship between the structure (i.e., phenotype) and sequence (i.e., genotype). RNA usually forms multiple substructures with similar thermodynamic stabilities, called structural fluctuations....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670806/ https://www.ncbi.nlm.nih.gov/pubmed/36195345 http://dx.doi.org/10.1261/rna.079291.122 |