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HITS-CLIP analysis of human ALKBH8 reveals interactions with fully processed substrate tRNAs and with specific noncoding RNAs

Transfer RNAs acquire a large plethora of chemical modifications. Among those, modifications of the anticodon loop play important roles in translational fidelity and tRNA stability. Four human wobble U–containing tRNAs obtain 5-methoxycarbonylmethyluridine (mcm(5)U(34)) or 5-methoxycarbonylmethyl-2-...

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Detalles Bibliográficos
Autores principales: Cavallin, Ivana, Bartosovic, Marek, Skalicky, Tomas, Rengaraj, Praveenkumar, Demko, Martin, Schmidt-Dengler, Martina Christina, Drino, Aleksej, Helm, Mark, Vanacova, Stepanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670814/
https://www.ncbi.nlm.nih.gov/pubmed/36192131
http://dx.doi.org/10.1261/rna.079421.122