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E. coli 6S RNA complexed to RNA polymerase maintains product RNA synthesis at low cellular ATP levels by initiation with noncanonical initiator nucleotides
The E. coli 6S RNA is an RNA polymerase (RNAP) inhibitor that competes with σ(70)-dependent DNA promoters for binding to RNAP holoenzyme (RNAP:σ(70)). The 6S RNA when bound is then used as a template to synthesize a short product RNA (pRNA; usually 13-nt-long). This pRNA changes the 6S RNA structure...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670815/ https://www.ncbi.nlm.nih.gov/pubmed/36198425 http://dx.doi.org/10.1261/rna.079356.122 |