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Methylation guide RNAs without box C/D motifs

Box C/D RNAs guide site-specific 2′-O-methylation of RNAs in archaea and eukaryotes. The defining feature of methylation guide RNAs is two sets of box C and D motifs that form kink-turn structures specifically recognized by L7Ae family proteins. Here, we engineered a new type of methylation guide th...

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Detalles Bibliográficos
Autores principales: Wang, Jiayin, Yang, Zuxiao, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670817/
https://www.ncbi.nlm.nih.gov/pubmed/36127125
http://dx.doi.org/10.1261/rna.079379.122