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A novel donor-derived cell-free DNA assay for the detection of acute rejection in heart transplantation

BACKGROUND: Endomyocardial biopsy (EMB), the reference surveillance test for acute rejection (AR) in heart transplant (HTx) recipients, is invasive, costly, and shows significant interobserver variability. Recent studies indicate that donor-derived cell-free DNA (dd-cfDNA), obtained non-invasively f...

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Detalles Bibliográficos
Autores principales: Kim, Paul J., Olymbios, Michael, Siu, Alfonso, Pinzon, Omar Wever, Adler, Eric, Liang, Nathan, Swenerton, Ryan, Sternberg, Jonathan, Kaur, Navchetan, Ahmed, Ebad, Chen, Yen-An, Fehringer, Gordon, Demko, Zachary P., Billings, Paul R., Stehlik, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670834/
https://www.ncbi.nlm.nih.gov/pubmed/35577713
http://dx.doi.org/10.1016/j.healun.2022.04.002