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5′ Untranslated mRNA Regions Allow Bypass of Host Cell Translation Inhibition by Legionella pneumophila

Legionella pneumophila grows within membrane-bound vacuoles in alveolar macrophages during human disease. Pathogen manipulation of the host cell is driven by bacterial proteins translocated through a type IV secretion system (T4SS). Although host protein synthesis during infection is arrested by the...

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Detalles Bibliográficos
Autores principales: Lipo, Erion, Asrat, Seblewongel, Huo, Wenwen, Sol, Asaf, Fraser, Christopher S., Isberg, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670960/
https://www.ncbi.nlm.nih.gov/pubmed/36321832
http://dx.doi.org/10.1128/iai.00179-22