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EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier

TJs maintain the epithelial barrier by regulating paracellular permeability. Since TJs are under dynamically fluctuating intercellular tension, cells must continuously survey and repair any damage. However, the underlying mechanisms allowing cells to sense TJ damage and repair the barrier are not ye...

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Detalles Bibliográficos
Autores principales: Higashi, Tomohito, Saito, Akira C., Fukazawa, Yugo, Furuse, Mikio, Higashi, Atsuko Y., Ono, Masahiro, Chiba, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671161/
https://www.ncbi.nlm.nih.gov/pubmed/36378161
http://dx.doi.org/10.1083/jcb.202204079