Synthesis, biological evaluation, and molecular docking of novel hydroxyzine derivatives as potential AR antagonists

Prostate cancer (PCa) is a malignant tumor with a higher mortality rate in the male reproductive system. In this study, the hydroxyazine derivatives were synthesized with different structure from traditional anti-prostate cancer drugs. In the evaluation of in vitro cytotoxicity and antagonistic acti...

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Detalles Bibliográficos
Autores principales: Qi, Yueheng, Xue, Baoli, Chen, Shijin, Wang, Wang, Zhou, Haifeng, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671208/
https://www.ncbi.nlm.nih.gov/pubmed/36405317
http://dx.doi.org/10.3389/fchem.2022.1053675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671208/
https://www.ncbi.nlm.nih.gov/pubmed/36405317
http://dx.doi.org/10.3389/fchem.2022.1053675

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