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Infectious origin of Alzheimer’s disease: Amyloid beta as a component of brain antimicrobial immunity

The amyloid cascade hypothesis, focusing on pathological proteins aggregation, has so far failed to uncover the root cause of Alzheimer’s disease (AD), or to provide an effective therapy. This traditional paradigm essentially explains a mechanism involved in the development of sporadic AD rather tha...

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Detalles Bibliográficos
Autores principales: Vojtechova, Iveta, Machacek, Tomas, Kristofikova, Zdenka, Stuchlik, Ales, Petrasek, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671327/
https://www.ncbi.nlm.nih.gov/pubmed/36395147
http://dx.doi.org/10.1371/journal.ppat.1010929