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Aging and sperm signals alter DNA break formation and repair in the C. elegans germline

Female reproductive aging is associated with decreased oocyte quality and fertility. The nematode Caenorhabditis elegans is a powerful system for understanding the biology of aging and exhibits age-related reproductive defects that are analogous to those observed in many mammals, including dysregula...

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Detalles Bibliográficos
Autores principales: Toraason, Erik, Adler, Victoria L., Libuda, Diana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671421/
https://www.ncbi.nlm.nih.gov/pubmed/36342909
http://dx.doi.org/10.1371/journal.pgen.1010282