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Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

Prion strains in a given type of mammalian host are distinguished by differences in clinical presentation, neuropathological lesions, survival time, and characteristics of the infecting prion protein (PrP) assemblies. Near-atomic structures of prions from two host species with different PrP sequence...

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Detalles Bibliográficos
Autores principales:	Hoyt, Forrest, Alam, Parvez, Artikis, Efrosini, Schwartz, Cindi L., Hughson, Andrew G., Race, Brent, Baune, Chase, Raymond, Gregory J., Baron, Gerald S., Kraus, Allison, Caughey, Byron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671466/ https://www.ncbi.nlm.nih.gov/pubmed/36342968 http://dx.doi.org/10.1371/journal.ppat.1010947

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