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Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery

With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have received enormous attention. However, due to the extreme instability and low intracellular gene expression of naked genes, speci...

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Detalles Bibliográficos
Autores principales: Wang, Hezhi, Qin, Lu, Zhang, Xin, Guan, Jian, Mao, Shirui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671523/
https://www.ncbi.nlm.nih.gov/pubmed/36372386
http://dx.doi.org/10.1016/j.jconrel.2022.10.061