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Mechanisms and challenges of nanocarriers as non-viral vectors of therapeutic genes for enhanced pulmonary delivery
With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have received enormous attention. However, due to the extreme instability and low intracellular gene expression of naked genes, speci...
Autores principales: | Wang, Hezhi, Qin, Lu, Zhang, Xin, Guan, Jian, Mao, Shirui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671523/ https://www.ncbi.nlm.nih.gov/pubmed/36372386 http://dx.doi.org/10.1016/j.jconrel.2022.10.061 |
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