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Structural effects of spike protein D614G mutation in SARS-CoV-2

A single mutation from aspartate to glycine at position 614 has dominated all circulating variants of the severe acute respiratory syndrome coronavirus 2. D614G mutation induces structural changes in the spike (S) protein that strengthen the virus infectivity. Here, we use molecular dynamics simulat...

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Detalles Bibliográficos
Autores principales: Dokainish, Hisham M., Sugita, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671695/
https://www.ncbi.nlm.nih.gov/pubmed/36397671
http://dx.doi.org/10.1016/j.bpj.2022.11.025