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Reduced Expression of Voltage-Gated Sodium Channel Beta 2 Restores Neuronal Injury and Improves Cognitive Dysfunction Induced by Aβ1-42

Voltage-gated sodium channel beta 2 (Nav2.2 or Navβ2, coded by SCN2B mRNA), a gene involved in maintaining normal physiological functions of the prefrontal cortex and hippocampus, might be associated with prefrontal cortex aging and memory decline. This study investigated the effects of Navβ2 in amy...

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Detalles Bibliográficos
Autores principales: Li, Shan, Yan, Guo-Ji, Tan, Ya-Xin, Xue, Lu-Lu, Wang, Ting-Hua, Zhao, Hao-Ran, Lu, Min-Nan, Zhang, Hui-Xiang, Mei, Rong, Dong, Xiao-Han, Liu, Li-Na, Wang, Dan, Xiyang, Yan-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671742/
https://www.ncbi.nlm.nih.gov/pubmed/36406589
http://dx.doi.org/10.1155/2022/3995227