Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization

Lung injury is one of the leading causes of death in sepsis. Abietic acid (AA) has demonstrated anti-inflammatory and bacteriostatic properties. Herein, we established a mouse model of sepsis by cecal ligation and puncture, and intraperitoneally injected AA to treat. Lung injury was assessed by H&am...

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Detalles Bibliográficos
Autores principales: Fang, Honglong, Chen, Juan, Luo, Jian, Hu, Jianhua, Wang, Danqiong, Lv, Liang, Zhang, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671762/
https://www.ncbi.nlm.nih.gov/pubmed/35644586
http://dx.doi.org/10.1538/expanim.22-0018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671762/
https://www.ncbi.nlm.nih.gov/pubmed/35644586
http://dx.doi.org/10.1538/expanim.22-0018

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