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Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization
Lung injury is one of the leading causes of death in sepsis. Abietic acid (AA) has demonstrated anti-inflammatory and bacteriostatic properties. Herein, we established a mouse model of sepsis by cecal ligation and puncture, and intraperitoneally injected AA to treat. Lung injury was assessed by H&am...
Autores principales: | Fang, Honglong, Chen, Juan, Luo, Jian, Hu, Jianhua, Wang, Danqiong, Lv, Liang, Zhang, Weiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671762/ https://www.ncbi.nlm.nih.gov/pubmed/35644586 http://dx.doi.org/10.1538/expanim.22-0018 |
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