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Establishment and application of a lethal model of an HRSV-long variant strain in BALB/c mice

Human respiratory syncytial virus (HRSV) is a major cause of lower respiratory tract infection in infants. The lack of ideal animal models is one of the major obstacles in evaluateing the efficacy of HRSV vaccines. In this study, HRSV-50 was obtained from Hep-2 cells at the 50th passage of the origi...

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Detalles Bibliográficos
Autores principales: LI, Hai, REN, Hu, CAO, Lei, GUO, Jinyuan, SONG, Jingjing, ZHANG, Yan, XU, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671768/
https://www.ncbi.nlm.nih.gov/pubmed/35732419
http://dx.doi.org/10.1538/expanim.22-0042