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The establishment and application of CD3E humanized mice in immunotherapy

In the field of cancer immunotherapy, monoclonal antibody drugs, bispecific antibodies, and antibody-conjugated drugs have become the focus of current research, and gene-edited animal models play an essential role in the entire drug development process. In this study, CD3E humanized mice were establ...

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Detalles Bibliográficos
Autores principales: Zhang, Rufeng, Zhang, Jing, Zhou, Xiaofei, Zhao, Ang, Yu, Changyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671771/
https://www.ncbi.nlm.nih.gov/pubmed/35570001
http://dx.doi.org/10.1538/expanim.22-0012