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Considerations in the design of animal infection pilot studies

Ethical research with experimental systems (animals or humans) requires a rationale for the number of subjects to be included in a study. Standard methods for estimating sample size are not fit-for-purpose when the experimenter cannot predict the effect size/outcome with any certainty. These types o...

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Detalles Bibliográficos
Autores principales: Laws, Thomas R., Maishman, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671774/
https://www.ncbi.nlm.nih.gov/pubmed/36405959
http://dx.doi.org/10.3389/fcimb.2022.948464