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Considerations in the design of animal infection pilot studies
Ethical research with experimental systems (animals or humans) requires a rationale for the number of subjects to be included in a study. Standard methods for estimating sample size are not fit-for-purpose when the experimenter cannot predict the effect size/outcome with any certainty. These types o...
Autores principales: | Laws, Thomas R., Maishman, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671774/ https://www.ncbi.nlm.nih.gov/pubmed/36405959 http://dx.doi.org/10.3389/fcimb.2022.948464 |
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