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Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline

A major unanswered question in the dementia field is whether cognitively unimpaired individuals who harbor both Alzheimer’s disease neuropathological hallmarks (that is, amyloid-β plaques and tau neurofibrillary tangles) can preserve their cognition over time or are destined to decline. In this larg...

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Detalles Bibliográficos
Autores principales: Ossenkoppele, Rik, Pichet Binette, Alexa, Groot, Colin, Smith, Ruben, Strandberg, Olof, Palmqvist, Sebastian, Stomrud, Erik, Tideman, Pontus, Ohlsson, Tomas, Jögi, Jonas, Johnson, Keith, Sperling, Reisa, Dore, Vincent, Masters, Colin L., Rowe, Christopher, Visser, Denise, van Berckel, Bart N. M., van der Flier, Wiesje M., Baker, Suzanne, Jagust, William J., Wiste, Heather J., Petersen, Ronald C., Jack, Clifford R., Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671808/
https://www.ncbi.nlm.nih.gov/pubmed/36357681
http://dx.doi.org/10.1038/s41591-022-02049-x