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N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA

Hepatic glycogen is the main source of blood glucose and controls the intervals between meals in mammals. Hepatic glycogen storage in mammalian pups is insufficient compared to their adult counterparts; however, the detailed molecular mechanism is poorly understood. Here, we show that, similar to gl...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Yin, Huilong, Zhang, Xiaofang, Jiang, Xunliang, Liu, Yongkang, Zhang, Haolin, Peng, Yingran, Li, Da, Yu, Yanping, Zhang, Jinbao, Cheng, Shuli, Yang, Angang, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671881/
https://www.ncbi.nlm.nih.gov/pubmed/36396934
http://dx.doi.org/10.1038/s41467-022-34808-2