Cargando…
New C3H Kit(N824K/WT) cancer mouse model develops late-onset malignant mammary tumors with high penetrance
Gastro-intestinal stromal tumors and acute myeloid leukemia induced by activating stem cell factor receptor tyrosine kinase (KIT) mutations are highly malignant. Less clear is the role of KIT mutations in the context of breast cancer. Treatment success of KIT-induced cancers is still unsatisfactory...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671887/ https://www.ncbi.nlm.nih.gov/pubmed/36396684 http://dx.doi.org/10.1038/s41598-022-23218-5 |