Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections

Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids and play an important role on host defense. It has been demonstrated that upon infection or intense liver inflammation, KCs might be severely depleted and replaced by immature monocytic cells; however, the...

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Detalles Bibliográficos
Autores principales: Hirako, Isabella C., Antunes, Maísa Mota, Rezende, Rafael Machado, Hojo-Souza, Natália Satchiko, Figueiredo, Maria Marta, Dias, Thomaz, Nakaya, Helder, Menezes, Gustavo Batista, Gazzinelli, Ricardo Tostes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671901/
https://www.ncbi.nlm.nih.gov/pubmed/36396745
http://dx.doi.org/10.1038/s41598-022-23858-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671901/
https://www.ncbi.nlm.nih.gov/pubmed/36396745
http://dx.doi.org/10.1038/s41598-022-23858-7

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