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Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections
Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids and play an important role on host defense. It has been demonstrated that upon infection or intense liver inflammation, KCs might be severely depleted and replaced by immature monocytic cells; however, the...
Autores principales: | Hirako, Isabella C., Antunes, Maísa Mota, Rezende, Rafael Machado, Hojo-Souza, Natália Satchiko, Figueiredo, Maria Marta, Dias, Thomaz, Nakaya, Helder, Menezes, Gustavo Batista, Gazzinelli, Ricardo Tostes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671901/ https://www.ncbi.nlm.nih.gov/pubmed/36396745 http://dx.doi.org/10.1038/s41598-022-23858-7 |
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