mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters

Chemotherapy can eradicate a majority of cancer cells. However, a small population of tumor cells often survives drug treatments through genetic and/or non-genetic mechanisms, leading to tumor recurrence. Here we report a reversible chemoresistance phenotype regulated by the mTOR pathway. Through a...

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Detalles Bibliográficos
Autores principales: Liu, Yuanhui, Azizian, Nancy G., Sullivan, Delaney K., Li, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671908/
https://www.ncbi.nlm.nih.gov/pubmed/36396656
http://dx.doi.org/10.1038/s41467-022-34890-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671908/
https://www.ncbi.nlm.nih.gov/pubmed/36396656
http://dx.doi.org/10.1038/s41467-022-34890-6

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