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mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
Chemotherapy can eradicate a majority of cancer cells. However, a small population of tumor cells often survives drug treatments through genetic and/or non-genetic mechanisms, leading to tumor recurrence. Here we report a reversible chemoresistance phenotype regulated by the mTOR pathway. Through a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671908/ https://www.ncbi.nlm.nih.gov/pubmed/36396656 http://dx.doi.org/10.1038/s41467-022-34890-6 |