Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models

Familial dysautonomia (FD), a rare neurodevelopmental and neurodegenerative disorder affects the sympathetic and sensory nervous system. Although almost all patients harbor a mutation in ELP1, it remains unresolved exactly how function of sympathetic neurons (symNs) is affected; knowledge critical f...

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Detalles Bibliográficos
Autores principales: Wu, Hsueh-Fu, Yu, Wenxin, Saito-Diaz, Kenyi, Huang, Chia-Wei, Carey, Joseph, Lefcort, Frances, Hart, Gerald W., Liu, Hong-Xiang, Zeltner, Nadja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671909/
https://www.ncbi.nlm.nih.gov/pubmed/36396637
http://dx.doi.org/10.1038/s41467-022-34811-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671909/
https://www.ncbi.nlm.nih.gov/pubmed/36396637
http://dx.doi.org/10.1038/s41467-022-34811-7

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