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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer
Cancer gene discovery is reliant on distinguishing driver mutations from a multitude of passenger mutations in tumour genomes. While driver genes may be revealed based on excess mutation recurrence or clustering, there is a need for orthogonal principles. Here, we take advantage of the fact that non...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671924/ https://www.ncbi.nlm.nih.gov/pubmed/36396655 http://dx.doi.org/10.1038/s41467-022-34746-z |