Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas

Ciliary neurotrophic factor (CNTF) acts as a potent neuroprotective cytokine in multiple models of retinal degeneration. To understand mechanisms underlying its broad neuroprotective effects, we have investigated the influence of CNTF on metabolism in a mouse model of photoreceptor degeneration. CNT...

Descripción completa

Detalles Bibliográficos
Autores principales: Do Rhee, Kun, Wang, Yanjie, ten Hoeve, Johanna, Stiles, Linsey, Nguyen, Thao Thi Thu, Zhang, Xiangmei, Vergnes, Laurent, Reue, Karen, Shirihai, Orian, Bok, Dean, Yang, Xian-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672129/
https://www.ncbi.nlm.nih.gov/pubmed/36396639
http://dx.doi.org/10.1038/s41467-022-34443-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672129/
https://www.ncbi.nlm.nih.gov/pubmed/36396639
http://dx.doi.org/10.1038/s41467-022-34443-x

Ejemplares similares