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Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
Ciliary neurotrophic factor (CNTF) acts as a potent neuroprotective cytokine in multiple models of retinal degeneration. To understand mechanisms underlying its broad neuroprotective effects, we have investigated the influence of CNTF on metabolism in a mouse model of photoreceptor degeneration. CNT...
Autores principales: | Do Rhee, Kun, Wang, Yanjie, ten Hoeve, Johanna, Stiles, Linsey, Nguyen, Thao Thi Thu, Zhang, Xiangmei, Vergnes, Laurent, Reue, Karen, Shirihai, Orian, Bok, Dean, Yang, Xian-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672129/ https://www.ncbi.nlm.nih.gov/pubmed/36396639 http://dx.doi.org/10.1038/s41467-022-34443-x |
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