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H2A.Z deposition by SWR1C involves multiple ATP-dependent steps

Histone variant H2A.Z is a conserved feature of nucleosomes flanking protein-coding genes. Deposition of H2A.Z requires ATP-dependent replacement of nucleosomal H2A by a chromatin remodeler related to the multi-subunit enzyme, yeast SWR1C. How these enzymes use ATP to promote this nucleosome editing...

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Detalles Bibliográficos
Autores principales: Fan, Jiayi, Moreno, Andrew T., Baier, Alexander S., Loparo, Joseph J., Peterson, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672302/
https://www.ncbi.nlm.nih.gov/pubmed/36396651
http://dx.doi.org/10.1038/s41467-022-34861-x