Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis

Multiple myeloma is a plasma cell malignancy almost always preceded by precursor conditions, but low tumor burden of these early stages has hindered the study of their molecular programs through bulk sequencing technologies. Here, we generate and analyze single cell RNA-sequencing of plasma cells fr...

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Detalles Bibliográficos
Autores principales: Boiarsky, Rebecca, Haradhvala, Nicholas J., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H., Zavidij, Oksana, Shih, Ming-Chieh, Firer, Danielle, Miller, Mendy, El-Khoury, Habib, Anand, Shankara K., Aguet, François, Sontag, David, Ghobrial, Irene M., Getz, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672303/
https://www.ncbi.nlm.nih.gov/pubmed/36396631
http://dx.doi.org/10.1038/s41467-022-33944-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672303/
https://www.ncbi.nlm.nih.gov/pubmed/36396631
http://dx.doi.org/10.1038/s41467-022-33944-z

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