Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis

Glucuronidation catalyzed by UDP-glucuronosyltransferases (UGTs) is one of the most important phase II mechanisms, facilitating drug clearance via conjugation of glucuronic acid with polar groups of xenobiotics. Accumulating evidence suggests that IBDs impact drug disposition, but whether and how IB...

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Detalles Bibliográficos
Autores principales: Zeng, Wanying, Liu, Xiaojing, Wu, Yangyang, Cai, Yuting, Li, Zhennan, Ye, Fei, Sun, Yuanhong, Li, Feng, Xing, Huijie, Wang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672319/
https://www.ncbi.nlm.nih.gov/pubmed/36408246
http://dx.doi.org/10.3389/fphar.2022.1053610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672319/
https://www.ncbi.nlm.nih.gov/pubmed/36408246
http://dx.doi.org/10.3389/fphar.2022.1053610

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