Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2

D/E repeats are stretches of aspartic and/or glutamic acid residues found in over 150 human proteins. We examined genomic stability of D/E repeats and functional characteristics of D/E repeat-containing proteins vis-à-vis the proteins with poly-Q or poly-A repeats, which are known to undergo patholo...

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Detalles Bibliográficos
Autores principales: Shukla, Shalabh, Lazarchuk, Pavlo, Pavlova, Maria N., Sidorova, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672403/
https://www.ncbi.nlm.nih.gov/pubmed/36404917
http://dx.doi.org/10.1016/j.isci.2022.105464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672403/
https://www.ncbi.nlm.nih.gov/pubmed/36404917
http://dx.doi.org/10.1016/j.isci.2022.105464

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