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Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2
D/E repeats are stretches of aspartic and/or glutamic acid residues found in over 150 human proteins. We examined genomic stability of D/E repeats and functional characteristics of D/E repeat-containing proteins vis-à-vis the proteins with poly-Q or poly-A repeats, which are known to undergo patholo...
Autores principales: | Shukla, Shalabh, Lazarchuk, Pavlo, Pavlova, Maria N., Sidorova, Julia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672403/ https://www.ncbi.nlm.nih.gov/pubmed/36404917 http://dx.doi.org/10.1016/j.isci.2022.105464 |
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