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N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains

The macrophage mannose receptor (MR, CD206) is a transmembrane endocytic lectin receptor, expressed in selected immune and endothelial cells, and is involved in immunity and maintaining homeostasis. Eight of the ten extracellular domains of the MR are C-type lectin domains (CTLDs) which mediate the...

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Detalles Bibliográficos
Autores principales: Stavenhagen, Kathrin, Mehta, Akul Y., Laan, Lisa, Gao, Chao, Heimburg-Molinaro, Jamie, van Die, Irma, Cummings, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672410/
https://www.ncbi.nlm.nih.gov/pubmed/36244450
http://dx.doi.org/10.1016/j.jbc.2022.102591