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N-glycosylation of mannose receptor (CD206) regulates glycan binding by C-type lectin domains
The macrophage mannose receptor (MR, CD206) is a transmembrane endocytic lectin receptor, expressed in selected immune and endothelial cells, and is involved in immunity and maintaining homeostasis. Eight of the ten extracellular domains of the MR are C-type lectin domains (CTLDs) which mediate the...
Autores principales: | Stavenhagen, Kathrin, Mehta, Akul Y., Laan, Lisa, Gao, Chao, Heimburg-Molinaro, Jamie, van Die, Irma, Cummings, Richard D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672410/ https://www.ncbi.nlm.nih.gov/pubmed/36244450 http://dx.doi.org/10.1016/j.jbc.2022.102591 |
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