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Control of cell surface expression of GABA(A) receptors by a conserved region at the end of the N-terminal extracellular domain of receptor subunits

Type A γ-aminobutyric acid receptors (GABA(A)Rs) represent a family of pentameric GABA-gated Cl(-)/HCO(3)(-) ion channels which mediate inhibitory transmission in the central nervous system. Cell surface expression of GABA(A)Rs, a prerequisite for their function, is dependent on the appropriate asse...

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Detalles Bibliográficos
Autores principales: Yuan, Banghao, Hatchett-Walker, Caroline, Long, Philip, Xu, Zhihan, Stephenson, F Anne, Haider, Shozeb, Jovanovic, Jasmina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672411/
https://www.ncbi.nlm.nih.gov/pubmed/36244453
http://dx.doi.org/10.1016/j.jbc.2022.102590