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PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma Proliferation

BACKGROUND & AIMS: Metabolic reprogramming, in particular, glycolytic regulation, supports abnormal survival and growth of hepatocellular carcinoma (HCC) and could serve as a therapeutic target. In this study, we sought to identify glycolytic regulators in HCC that could be inhibited to prevent...

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Detalles Bibliográficos
Autores principales: Dou, Qianhui, Grant, Aaron K., Callahan, Cody, Coutinho de Souza, Patricia, Mwin, David, Booth, Adam L., Nasser, Imad, Moussa, Marwan, Ahmed, Muneeb, Tsai, Leo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672450/
https://www.ncbi.nlm.nih.gov/pubmed/36162723
http://dx.doi.org/10.1016/j.jcmgh.2022.09.009