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Arginine Methylation of Integrin Alpha-4 Prevents Fibrosis Development in Alcohol-Associated Liver Disease

BACKGROUND & AIMS: Alcohol-associated liver disease (ALD) comprises a spectrum of disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. We aimed to study the role of protein arginine methyltransferase 6 (PRMT6), a new regulator of liver function, in ALD progression. METHODS: P...

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Detalles Bibliográficos
Autores principales: Schonfeld, Michael, Villar, Maria T., Artigues, Antonio, Weinman, Steven A., Tikhanovich, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672451/
https://www.ncbi.nlm.nih.gov/pubmed/36191854
http://dx.doi.org/10.1016/j.jcmgh.2022.09.013