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Protein Tyrosine Kinase 7 (PTK7) Promotes Metastasis in Hepatocellular Carcinoma via SOX9 Regulation and TGF-β Signaling

BACKGROUND & AIMS: Metastasis is found in most advanced hepatocellular carcinoma (HCC) patients, and it drives tumor recurrence and systemic failure. There is no effective treatment owing to its complex biological features. Many of the molecular drivers of metastasis are crucial players in norma...

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Detalles Bibliográficos
Autores principales: Wong, Tsz Lam Matthew, Wong, Tin-Lok, Zhou, Lei, Man, Kwan, Purcell, James, Lee, Terence K., Yun, Jing-Ping, Ma, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672488/
https://www.ncbi.nlm.nih.gov/pubmed/36202326
http://dx.doi.org/10.1016/j.jcmgh.2022.09.015