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Protein Tyrosine Kinase 7 (PTK7) Promotes Metastasis in Hepatocellular Carcinoma via SOX9 Regulation and TGF-β Signaling
BACKGROUND & AIMS: Metastasis is found in most advanced hepatocellular carcinoma (HCC) patients, and it drives tumor recurrence and systemic failure. There is no effective treatment owing to its complex biological features. Many of the molecular drivers of metastasis are crucial players in norma...
Autores principales: | Wong, Tsz Lam Matthew, Wong, Tin-Lok, Zhou, Lei, Man, Kwan, Purcell, James, Lee, Terence K., Yun, Jing-Ping, Ma, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672488/ https://www.ncbi.nlm.nih.gov/pubmed/36202326 http://dx.doi.org/10.1016/j.jcmgh.2022.09.015 |
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