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The GPCR properties of polycystin-1- A new paradigm

Polycystin-1 (PC1) is an 11-transmembrane (TM) domain-containing protein encoded by the PKD1 gene, the most frequently mutated gene leading to autosomal dominant polycystic kidney disease (ADPKD). This large (> 462 kDal) protein has a complex posttranslational maturation process, with over five p...

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Detalles Bibliográficos
Autores principales: Maser, Robin L., Calvet, James P., Parnell, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672506/
https://www.ncbi.nlm.nih.gov/pubmed/36406261
http://dx.doi.org/10.3389/fmolb.2022.1035507