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The GPCR properties of polycystin-1- A new paradigm

Polycystin-1 (PC1) is an 11-transmembrane (TM) domain-containing protein encoded by the PKD1 gene, the most frequently mutated gene leading to autosomal dominant polycystic kidney disease (ADPKD). This large (> 462 kDal) protein has a complex posttranslational maturation process, with over five p...

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Detalles Bibliográficos
Autores principales:	Maser, Robin L., Calvet, James P., Parnell, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672506/ https://www.ncbi.nlm.nih.gov/pubmed/36406261 http://dx.doi.org/10.3389/fmolb.2022.1035507

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